05e847e98b6f0989…

Study
ID: NCT000404431,005 bytesFirst seen Jun 12, 20261 collection

Fields

NameValue
briefSummaryGlutamate is fundamentally involved in learning and memory. Memory loss associated with mild cognitive impairment may be due to loss of glutamate receptors in the aging brain. There is evidence CX516 enhances brain activity by specifically targeting remaining glutamate receptors in the affected portions of the brain. This study will test the safety and efficacy of CX516 in the symptomatic treatment of participants with mild cognitive impairment.
completionDate2004-06
conditions["Mild Cognitive Impairment"]
enrollmentCount175
enrollmentTypeACTUAL
nctIdNCT00040443
phasePHASE2
sponsorIdrespirerx
startDate2002-04
statusCOMPLETED
studyTypeINTERVENTIONAL
titleEfficacy And Safety Of CX516 (900 mg t.i.d.) In Elderly Participants With Mild Cognitive Impairment. A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group 4-week Study.
urlhttps://clinicaltrials.gov/study/NCT00040443

Canonical JSON

{
  "id": "NCT00040443",
  "type": "Study",
  "data": {
    "briefSummary": "Glutamate is fundamentally involved in learning and memory. Memory loss associated with mild cognitive impairment may be due to loss of glutamate receptors in the aging brain. There is evidence CX516 enhances brain activity by specifically targeting remaining glutamate receptors in the affected portions of the brain. This study will test the safety and efficacy of CX516 in the symptomatic treatment of participants with mild cognitive impairment.",
    "completionDate": "2004-06",
    "conditions": [
      "Mild Cognitive Impairment"
    ],
    "enrollmentCount": 175,
    "enrollmentType": "ACTUAL",
    "nctId": "NCT00040443",
    "phase": "PHASE2",
    "sponsorId": "respirerx",
    "startDate": "2002-04",
    "status": "COMPLETED",
    "studyType": "INTERVENTIONAL",
    "title": "Efficacy And Safety Of CX516 (900 mg t.i.d.) In Elderly Participants With Mild Cognitive Impairment. A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group 4-week Study.",
    "url": "https://clinicaltrials.gov/study/NCT00040443"
  }
}

Appears in 1 collection

nih/clinical-trials1 version · Jun 12, 2026

Full hash:05e847e98b6f09898e9bc2620a4eb465cc568cb3435e17f47d53087c6d914c43