48171a2dfdaa3ae4…

Study
ID: NCT001044421,161 bytesFirst seen Jun 12, 20261 collection

Fields

NameValue
briefSummaryAlzheimer's disease is a medical illness that damages the brain and causes problems with memory, mood and behavior. A substance called acetylcholine (ACh), which is naturally produced in the body, plays an important role in the normal functioning of the brain. In subjects with Alzheimer's disease, the level of ACh is greatly reduced. Currently, there are three commonly prescribed drugs used for treating the symptoms of Alzheimer's disease by helping to maintain the level of ACh in the brain. This study will evaluate how much each of these drugs changes the levels of certain brain chemicals that are known to, or may play an important role in, Alzheimer's disease and its symptoms.
completionDate2006-04
conditions["Alzheimer's Disease"]
enrollmentCount80
enrollmentTypenull
nctIdNCT00104442
phasePHASE4
sponsorIdnovartis
startDate2003-10
statusCOMPLETED
studyTypeINTERVENTIONAL
titleStudy of the Effects of Current Drug Treatments on Levels of Certain Brain Chemicals in Alzheimer's Disease
urlhttps://clinicaltrials.gov/study/NCT00104442

Canonical JSON

{
  "id": "NCT00104442",
  "type": "Study",
  "data": {
    "briefSummary": "Alzheimer's disease is a medical illness that damages the brain and causes problems with memory, mood and behavior. A substance called acetylcholine (ACh), which is naturally produced in the body, plays an important role in the normal functioning of the brain. In subjects with Alzheimer's disease, the level of ACh is greatly reduced. Currently, there are three commonly prescribed drugs used for treating the symptoms of Alzheimer's disease by helping to maintain the level of ACh in the brain. This study will evaluate how much each of these drugs changes the levels of certain brain chemicals that are known to, or may play an important role in, Alzheimer's disease and its symptoms.",
    "completionDate": "2006-04",
    "conditions": [
      "Alzheimer's Disease"
    ],
    "enrollmentCount": 80,
    "enrollmentType": null,
    "nctId": "NCT00104442",
    "phase": "PHASE4",
    "sponsorId": "novartis",
    "startDate": "2003-10",
    "status": "COMPLETED",
    "studyType": "INTERVENTIONAL",
    "title": "Study of the Effects of Current Drug Treatments on Levels of Certain Brain Chemicals in Alzheimer's Disease",
    "url": "https://clinicaltrials.gov/study/NCT00104442"
  }
}

Appears in 1 collection

nih/clinical-trials1 version · Jun 12, 2026

Full hash:48171a2dfdaa3ae4cf2c08e9b9c23c941f6cd895568f607093bf2eb87ca233e7