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{
  "id": "NCT00001972",
  "type": "Study",
  "data": {
    "briefSummary": "The main source of energy for the brain comes from a combination of oxygen and glucose (sugar). For brain cells to function normally they must receive a constant supply of these nutrients. As areas of the brain become more active blood flow into and out of these areas increase.\n\nIn addition to oxygen and glucose, the brain uses chemical compounds known as phospholipids. These phospholipids make up the covering of nerve cells that assist in the transfer of information from cell to cell. Without phospholipids brain cell activity may become abnormal and cause problems in the nervous system.\n\nCertain diseases like Alzheimer's disease and brain tumors can affect blood flow to the brain and change the way the brain metabolizes phospholipids. In addition to diseases, changes in the brain occur with normal healthy aging.\n\nThis study is designed to use PET scan to measure changes in blood flow and changes in phospholipid metabolism. Using this technique, researchers can improve their understanding of how certain diseases change the shape and function of the brain.",
    "completionDate": "2002-08",
    "conditions": [
      "Alzheimer's Disease",
      "Brain Neoplasm",
      "Niemann Pick Disease"
    ],
    "enrollmentCount": 123,
    "enrollmentType": null,
    "nctId": "NCT00001972",
    "phase": null,
    "sponsorId": "national-institute-of-neurological-disorders-and-stroke-ninds",
    "startDate": "1994-09",
    "status": "COMPLETED",
    "studyType": "OBSERVATIONAL",
    "title": "Positron Emission Tomography Imaging of Human Brain Phospholipid Metabolism in Relation to Age and Disease",
    "url": "https://clinicaltrials.gov/study/NCT00001972"
  }
}